Antibaterial Activity Of Aqueous And Ethanolic Leaf Extracts Of <i>Peperomia pellucida</i> (L.) H. B. & K. (Piperaceae) On Three Gram-Negative Bacteria Isolates.

  • Akinnibosun H. A. Department of Plant Biology and Biotechnology, University of Benin
  • Akinnibosun F. I. Department of Plant Biology and Biotechnology, University of Benin
  • German B. E. Department of Plant Biology and Biotechnology, University of Benin

Abstract

The antibacterial activity of aqueous and ethanolic  leaf extract of Peperomia pellucida was investigated on Escherichia coli,  Proteus mirabilis and Pseudomonas  aeruginosa using Agar-well diffusion method. Results showed that E. coli displayed the highest susceptibility in water extract (17.4mm–21.2mm) followed  by P. mirabilis (12.4mm–15mm) and  least in P. aeruginosa (10.2mm–12.24mm).  Conversely, the ethanolic extract showed the highest inhibition in P. aeruginosa (13.4mm–19.6mm) followed  by Proteus mirabilis (10.2mm–18.2mm)  and the least was in Escherichia coli (0.0mm–12.2mm).  The results revealed that ethanol is better than water as solvent for  extraction of P. pellucida for it to show its highest inhibitory activity on Proteus mirabilis and P. aeruginosa while water is the best  solvent for extraction of P. pellucida forit to show its highest inhibitory  activity on E. coli